Reward processing in patients with anhedonia, and the relationship between dopamine and motivation.
The TReAD Lab studies the behavioral and neurobiological determinants of cost/benefit decision-making in healthy individuals, as well as in patients with mental illness. Our research focuses on the neural circuitry that underlies decision-making and how abnormalities in these processes relate to and manifest as core symptoms in affective disorders, like major depressive disorder.
Exploring the neural circuitry that underlies cost/benefit decision-making
We study the contribution of Inflammation to dopamine dysfunction and motivational impairments in psychiatric illness as well as
medial prefrontal glutamate responses during stress and reinforcement learning in depression.